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And they stimulate insulin release in a glucose-dependent way, which is why they lower blood sugar in diabetics without generally causing hypoglycaemia

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[7] GLP1R is composed of two domains, one extracellular (ECD) that binds the C-terminal helix of GLP-1, [8] and one transmembrane domain (TMD) [9] that binds the N-terminal region of GLP-1